Pharmacy Curriculum Outcomes Assessment (PCOA) Practice Exam

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For Acyclovir to be effective against herpes simplex 1 virus, the virus must be:

  1. Dormant

  2. Replicating

  3. Mutating

  4. In the lysogenic phase

The correct answer is: Replicating

Acyclovir works by preventing the replication of the herpes simplex 1 virus. This means that it is most effective when the virus is actively reproducing. If the virus is dormant or in the lysogenic phase, it is not actively replicating itself, and therefore Acyclovir would not be as effective. Mutations can also make the virus less susceptible to the drug, but the most crucial factor for Acyclovir's effectiveness is that the virus is in the active replicating phase.

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